Hanyu Pan
Greetings! I am a junior studying Materials Science & Engineering. I'm interested in computational simulation of materials, and I want to pursue a PhD in this direction. I have prior research experience working with Dr. Thomas O'Connor on molecular dynamics simulation of copolymer force-extension behavior. My current research project supervised by Dr. Rebecca Taylor focuses on adapting the shape annealing algorithm (developed by her former Ph.D student Dr. Bolutito Babatunde) to arbitrary bp resolution, which allows automating design of DNA origami on different lattice.
Current Projects
- Redesigned the shape grammar of the shape annealing algorithm so that it can automate design on an arbitrary lattice. Users can now specify bp resolution and lattice structure. This semester, we want to generate origami on a square lattice and use coarse-grained modeling to study its thermodynamic and mechanical stability.
Previous Experience
- Impact of Hydropobic Sequencing on the Force-Extension Behavior of Copolymer: My previous research with Dr. Thomas O'Connor focusd on using molecular dynamic simulation to characterize phase transition in a single chain copolymer made of hydrophilic and hydrophobic monomers under different temperatures and tensile forces. I learned to perform bias sampling, use Landeau theory, and apply numerical techniques (Multi-Bennett Acceptance Ratio) to map the free energy landscape of coil to globule phase transition. I'm familiar with single-chain polymer physics and statistical thermodynamics, while proficient in Python coding and statistical modeling.
Contact Information
- Please contact me by email: hanyup@andrew.cmu.edu