Aleyamma Alexander, Ph.D.
I am currently a Postdoctoral Research Associate in the Mechanical Engineering Department at Carnegie Mellon University, working in the Microsystems and Mechanobiology Lab. My doctoral research focused on neodymium-based nanocarriers that are functionalized with folate and cyclodextrin, and are effective in breast cancer treatment.
Current Projects
Currently analyzing how DNA nanostructures play a role in targeted delivery for therapy.
Previous Experience
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Assistant Professor | Centre for Nanoscience and Genomics | Karunya Institute of Technology and Sciences, Tamilnadu, India July 2022 - June 2023
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Research Fellow and Teaching Research Assistant | Centre for Nanoscience and Genomics | Karunya Institute of Technology and Sciences, Tamilnadu, India | Project Funded by Board of Research and Nuclear Sciences - Department of Atomic Energy (DAE), Mumbai, India. Sep 2018 -Aug 2021 Project Title: Porphyrin–Tethered–β-Cyclodextrin Loaded with Guanidinobenzimidazoles as G-Quadruplex DNA Binders: Interplay of Different Modes of Binding
Patents
- I. V. M. V. Enoch, A. Alexander, A Composition for Preparing Electrospun Polymeric Nanofibre Mat for Preparing Face Mask for Antimicrobial Use, Vide Patent Application No. 202041024059, Dated 08.06.2020, Indian Patent.
- S.Thankappan, A. Alexander, P.Sridhar, Nanoemulsion based bioformulation for stage specific application of bio-inoculants (filing under process).
Fellowships
- Karunya Short Term Research Grant, Feb 2023
- Research Fellowship, Project Funded by Board of Research and Nuclear Sciences (37(2)/14/17/2018-BRNS)
- Student Fellowship (M.Tech.), Department of Science and Technology (Goverment of India)-Nanomission Project Scheme (SR/NM/PG-04/2008),July 2010
Publications
- Alexander, A.; Pillai, A. S.; Nallamuthu, A.; Pal, H.; Enoch, I. V. M. V.; Sayed, M. G-Quadruplex selectivity and cytotoxicity of a guanidine-encapsulated porphyrin-cyclodextrin conjugate. Int. J. Biol. Macromol. 2022, 218, 839-855
- Alexander, A.; Pillai, A. S.; Varalakshmi, G. S.; Ananthi, N.; Pal, H.; Enoch, I. V. M. V.; Sayed, M. G-Quadruplex binding affinity variation on molecular encapsulation of ligands by porphyrin-tethered cyclodextrin. J. Mol. Liq. 2023, 373, 121233.
- Alexander, A.; Sumohan Pillai, A.; Manikantan, V.; Sri Varalakshmi, G.; Allben Akash, B.; Enoch, I. V. M. V. Magnetic and Luminescent Neodymium-Doped Carbon Dot- Cyclodextrin Polymer Nanocomposite as an Anticancer Drug-Carrier. Mater. Lett. 2022, 313.
Contact Information
- Please contact me by email: aleyamma@andrew.cmu.edu
- Google Scholar