Ge Yang
Assistant Professor, Department of Biomedical Engineering
Assistant Professor, Lane Center for Computational Biology
Contact Information
|
Office |
Laboratory |
|
Lane Center for
Computational Biology Mellon Institute Email: geyang at
andrew dot cmu dot edu Phone:
412-268-3186 Fax: 412-268-2977 |
Computational Cell Dynamics Laboratory Mellon Institute
280 4400 Fifth Ave. |
Positions Available for Ph.D.
Students
I am actively seeking outstanding graduate students
to join my lab in academic year 2010.
Prospective students may apply through either the Biomedical Engineering Department or the CMU-Pitt Joint PhD Program in Computational
Biology. In the meantime, you are also encouraged to send your CV to Dr. Ge Yang.
Education
B.S. Mechanical Engineering & B.S. Electrical
Engineering, Tsinghua University,
1986-1991
M.S. Electrical Engineering, Institute of Automation, Chinese Academy of
Sciences, 1995-1998
M.S., Ph.D. (with Dr. Bradley Nelson), Mechanical
Engineering, University of Minnesota Twin Cities,
1998-2004
Postdoctoral Training (with Dr. Gaudenz Danuser), Computational Cell
Biology, Scripps Research Institute,
2004-2008
Honors and Awards
§
Wimmer
Faculty Fellow, Wimmer Foundation and Eberly Center for Teaching
Excellence, Carnegie Mellon University, 2009
§
Nomination
for Burroughs-Wellcome Interfaces in Science Award,
Scripps Research Institute, 2007
§
Burroughs-Wellcome
LJIS Interdisciplinary Fellowship, Burroughs-Wellcome Fund, 2006-2007
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Excellent
Student Award, Institute of Automation, Chinese Academy of
Sciences, 1997
§
Elite
Fellowship, Chinese Academy of Sciences, 1996
§
Guanghua
Fellowship, Tsinghua University, 1989
Research Program Affiliations
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Department of
Biomedical Engineering
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Center for
Bioimage Informatics
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Lane Center
for Computational Biology
§
Carnegie
Mellon University & University of Pittsburgh Joint Program in Computational
Biology
Research Interests
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Computer vision techniques for automated quantitative
analysis of fluorescence image data
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Imaging-based mapping, analysis, and modeling of spatial-temporal
dynamics of cell signaling and the cytoskeleton
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Molecular mechanics of the cytoskeleton
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Single molecule fluorescence imaging
Teaching
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Spring 2009: Current Topics in Computational
Biology
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Fall 2009: Engineering Molecular Cell
Biology
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Spring 2010: Bioimaging Informatics (TBD)
Selected Publications
Journal Articles
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Houghtaling
B.R., Yang G.*,
Matov A.*,
Danuser G., and Kapoor T. (2009) Op18 reveals the contribution of
non-kinetochore microtubules to the dynamic organization of the vertebrate
meiotic spindle, Proc. Natl. Acad.
Sci., to appear.
§ Yang G.*, Cameron L.A.*, Danuser G., and Salmon E.D. (2008) Regional variation of microtubule flux reveals microtubule organization in Xenopus extract meiotic spindles, Journal of Cell Biology, vol. 182, pp. 631-639.
§ Yang G.*, Houghtaling B.R.*, Gaetz J., Liu J.Z., Danuser G., and Kapoor T.M. (2007), Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging, Nature Cell Biology, vol. 9, pp. 1233-1242. (*equal contribution)
§ Haghnia M., Cavalli V., Shah S.B., Schimmelpfeng K., Brusch R., Yang G., Herrera C., Pilling A., and Goldstein, L.S.B. (2007), Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment, Molecular Biology of the Cell, vol. 18, pp. 2081-2089.
§ Cameron L.A., Yang G., Cimini D., Canman J.C., Kisurina-Evgenieva O., Khodjakov A., Danuser G., and Salmon E.D. (2006) A pulling-in mechanism produces the majority of kinetochore microtubule poleward flux in PtK1 cells, Journal of Cell Biology, vol. 173, pp. 173-179. (Cover)
§ Yang G. and Nelson B.J. (2005) Optomechatronic design of microassembly systems for manufacturing hybrid microsystems, IEEE Transactions on Industrial Electronics, vol. 52, pp. 1013-1023.
§ Yang G., Gaines J.A., and Nelson B.J. (2003) A supervisory wafer-level microassembly system for hybrid MEMS fabrication, Journal of Intelligent and Robotic Systems, vol. 37, pp. 43-68.
§
Vikramaditya
B., Nelson B.J., Yang G., and Enikov
E.T. (2001) Microassembly of hybrid magnetic M
Reviews & Book Chapters
§ Cameron, L.A., Houghtaling, B.R., and Yang G. (2009) Fluorescent Speckle Microscopy, in Optical Imaging Techniques: a Laboratory Manual, Yuste R. eds., Cold Spring Harbor Laboratory Press, to appear.
§ Applegate, K., Yang G., Danuser, G. (2008) Measuring the dynamic cytoskeleton architecture in living cells, in Nanomedicine and Nanobiotechnology, Vogel V. et al. eds., Wiley-VCH, to appear.
§ Dorn J., Danuser G., and Yang G. (2007) Computational processing and analysis of dynamic fluorescence image data, (invited) in Fluorescent Proteins, Methods in Cell Biology, vol. 85, pp. 497-538.
§ Yang G. and Nelson, B.J. (2007) Fundamentals of microscopy and machine vision, in Life Science Automation: Fundamentals and Applications, Zhang M.J., Nelson B.J., and Felder R.A. eds., pp.125-149, Artech House.
§ Shah S., Yang G., Danuser G., and Goldstein L.S.B. (2006) Axonal transport: imaging and modeling of a neuronal process, in Proc. Nobel Symposium 131: Controlled Nanoscale Motion in Biological and Artificial Systems. Lecture Notes in Physics, vol. 711, pp. 65-84, Springer-Verlag.
§ Yang G. and Nelson B.J. (2003) Automated microassembly, in MEMS Packaging, T.-R. Hsu ed., pp. 109-140, IEE Press.
Peer-Reviewed Conference Papers
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Yang G., Matov A., and
Danuser G. (2005) Reliable tracking of large-scale dense particle motion for
fluorescent live cell imaging. Proc.
Workshop on Computer Vision Methods for Bioinformatics, IEEE Int. Conf.
Computer Vision and Pattern Recognition. pp. 9-17.
§
Yang G. and Nelson
B.J. (2003) Wavelet-based autofocusing and unsupervised segmentation of
microscopic images. Proc. IEEE/RSJ
Int. Conf. Intelligent Robots and Systems, vol. 3, pp. 2143-2148.
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Yang G. and Nelson
B.J. (2003) Micromanipulation contact transition control by selective focusing
and microforce control. Proc. IEEE
Int. Conf. Robotics and Automation, vol. 3, pp. 3200-3206.
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Yang G. and Nelson
B.J. (2002) Integration of microscopic vision and microforce feedback for
microassembly. Proc. 3rd Int. Workshop
on Microfactories, pp. 145-148.
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Greminger
M., Yang G., and Nelson B.J. (2002)
Sensing nanonewton level forces by visually tracking structural deformations. Proc. IEEE Int. Conf. Robotics and
Automation, vol. 2, pp. 1943-1948.
§
Yang G., Gaines J.A.,
and Nelson B.J. (2001) A flexible experimental workcell for efficient and
reliable wafer-level 3D microassembly. Proc.
IEEE Int. Conf. on Robotics and Automation, vol. 1, pp. 133-138.
© Ge Yang, Carnegie Mellon
University, 2009
This webpage is under constant
construction.